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The Metropolitan Cathedral of the Great Holy Virgin (Megali Panagia) in Rethymno is dedicated to the Presentation of the Virgin Mary (feast 21st November) and is called great to distinguish it from Little Virgin Mary (Mikri Panagia). The original building was a three-aisled basilica with the middle aisle dedicated to the Presentation of the Virgin Mary and the other two to the Three Hierarchs and the Holy Apostles. This church was founded in 1844 and was completed in 1856, under the guidance of the bishop Kallinikos Nikoletakis.
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