The cave of Aghios Antonios near the village of Patsos also represents a place of dedication as has been proved by archaeological research.

It was used as an important centre of worship from the Late Minoan up until the Roman period. An inscription that was found in the cave testifies that Hermes Kraneos was worshipped here. The church in the interior of the cave is dedicated to Aghios Antonios, the patron of the children. The cave is open to visitors.